Dabur Research Foundation Blogs

  “Your body will be around a lot more than an expensive handbag. Invest in yourself”- Anonymous Advanced technology has been a boon to human mankind but it has also proved to be a curse. Technology has led to changed lifestyle which in turn has caused the tremendous evolution of the chronic diseases and thus the burden on the human mankind. Worldwide, large population suffers from one or the other disease, thus, having unhealthy body. Wellness is a state of physical, emotional, sexual and cognitive health wherein the body is in a state of balance. It can be measured by estimating the expression levels of various biomarkers that are pre-requisite for a healthy lifestyle. Any offset of these biomarkers can lead to unhealthy state of the body. Biomarkers are defined as biological molecules which are found in body fluids such as blood, urine, CSF or tissues and are indicative of a normal or an abnormal process in the body. They are often used to predict well-being of the body an...

                                   "Quality is not an act, it is a habit"- Aristotle Contract Research Organizations (CRO) are meant to provide services to the industries related to Biotechnology, Agrochemicals, and Pharmaceutical products and at times for Medical devices too. Usually, CROs are divided into drug discovery, preclinical, clinical, and laboratory services out of which most of them are related to safety studies. In the current competitive environment of the drug development process, CROs can play a crucial role to reduce costs for product development and save time as well. Eventually, all the generated data must submit somewhere which we term as regulatory agencies for the final product approval. Harmonization plays an important role in the acceptance of this data which is governed by following related policies and guidelines precisely, by Good Laboratory Practices (GLP) published ...

Let give ourselves an opportunity to live a healthy lifestyle by improving our immunity through a nutritious diet rich in vitamins, minerals, and other nutrients that our body require. It doesn't mean you won't become sick, but you'll be healthier and more resistant to disease. Boost the immune system, how? The gastrointestinal system, which comprises all the microbes that reside there, is where your immune response develops. Your stomach is full of beneficial bacteria when it's functional, that enhances our immune function. Allow immunity to take a chance. Get all immunizations that are indicated. They help the immune system detect infections and combat them before they spread throughout the body. Furthermore, antioxidants are one of the best sources of immunity boosters . Antioxidants are compounds found in fruits, vegetables, teas, and other foods that aid in the fight against oxidative stress.    Have you ever Heard of Immunomodulators?    Immunomodulators a...

Liver is the largest solid internal organ. It performs more than 400 tasks to keep the body healthy. The most important are metabolism. The liver filters everything that is eaten or consumed, whether it is food, alcohol, medicine, or toxins. Food is digested by the stomach and intestine, absorbed into the blood, and then transported to the liver. The liver is clever. It knows when to detoxify, when to excrete toxins via urine or stool, when to store nutrients, and when to bring back them into the blood. The human liver is an amazing organ. Every day, it produces bile, converts nutrients from your diet, removes toxins from your blood, breaks down fats, alcohol, and medications, regulates blood sugar and hormone levels, stores iron, and does a variety of other things. What happens if the liver fails? Liver failure can affect many of your body's organs. Acute liver failure can result in infections, electrolyte deficiencies, and bleeding. Without treatment, both acute and chronic li...

  "Animal Testing is needless, especially in cosmetics"- Leona Lewis Every year, over 100 millions of animals including mice, rats, frogs, dogs, cats, rabbits, hamsters, guinea pigs, monkeys, fish, and birds etc are killed in laboratories across the globe for various reasons such as biology lessons, medical training, and testing of chemicals, drugs, food and cosmetics. They are forced to inhale toxic fumes, or restrained and starved for hours, some have holes drilled into their skulls, and others have their skin burned off or their spinal cords crushed. Basically, live animals are treated like disposable laboratory equipment. Over the years, animal activists have been raising their voice to curb the use of animals for testing purposes especially cosmetics. In past, animals have been widely used to assess the safety and toxicity of cosmetic products and their ingredients. However, the trend is now changing. In 2010, the EU Directive 2010/63/EU on the protection of animals ...

"All substances are poisons; there is none which is not a poison. The right dose differentiates a poison"- Paracelsus Anciently toxicology was known as the ‘Science of Poison,’ now a days it is defined as the study of the effect of chemicals on living organisms and their evaluation as whether these entities are harmful or not or estimating a safe range. For the establishment of safety margins from the adverse effects of chemicals, toxicology depends on a few factors like dosage, route of exposure, dosing regimen, fate of the chemical and their biotransformation. The safety level of chemical is picked by the execution of sets of step wise experiments. Toxicology plays a major part in the drug development process to determine the safe dose and drug response on an exposed organism. It includes four disciplines like biology, chemistry, pharmacology and lastly medicine with an intervention of information technology up to some extent. In the current scenario toxicology studies...